Student Solution

-->

"Education is the most powerful weapon which you can use to change the world”
– Nelson Mandela

1 University

1 Course

1 Subject

Week 8 Lab Conversation

Week 8 Lab Conversation

Q This Week's Posting Prompt: The lab discussion assignment this week is to review peer-reviewed scientific literature on the "Hygiene hypothesis" and autoimmune diseases, then address the prompt below. See Lab 8 for the background information. Perform literature searches in the databases and search engines suggested in Table 2.1 of Section 2.4 in your Writing in Biology handbook. We recommend starting with Web of Science or Google Scholar. Refer to Section 2.2 of your handbook as a guide to help you get started. If you have questions about interesting articles you’ve found, please post those here too. 1. Find an additional paper from the peer-reviewed literature on the hygiene hypothesis and/or autoimmune diseases, and post the full citation (and a link to the source if available). In addition, provide a two or three sentence synopsis from the study that states: a. What was the purpose of the study? b. What did they conclude? ________________________________________ General Guidance: You should read through this week's assigned lab and/or Peerceptiv material before you make your post, so that your post will be informed, and you avoid posing a question that is answered in the course materials. General Format: You are required to make ONE post to each week’s lab discussion board. Your required post must contain 50 words at minimum and be written in your own words. Your grade will be determined by your demonstration of three areas of communication: application, critical thinking, and writing. Deadline: Your required post is due by 11:59PM, Wednesday. Late posts will be penalized 0.5 points (20%) per day late. NOTE: We recommend that you avoid using the smartphone/tablet Canvas app when submitting your conversation post, because the app frequently fails to associate posts with your corresponding conversation group.

View Related Questions

Solution Preview

• The study explores the uses of Anti-CD38 antibody therapy for treating systemic autoimmune disease. CD38 are type II glycoproteins that play an essential role in signal transduction and cell adhesion. These glycoproteins are among the plasmablasts that are antibody-producing B cells. These CD38 are observed to be an effective target to treat autoantibodies. The study shows that targeting the B cells and depleting their number effectively treats various kinds of systemic autoimmune diseases. For instance, a similar treatment targeting the CD20 antibody using the rituximab proved to be beneficial in treating autoimmune diseases.